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Cancer Treatment and Research: Coagulation in Cancer, 1st Edition
By David Green, Hau C. Kwaan

* Publisher: Springer
* Number Of Pages: 320
* Publication Date: 2009-04-24
* ISBN-10 / ASIN: 0387799613
* ISBN-13 / EAN: 9780387799612
* Binding: Hardcover
* Format: PDF

Steven T. Rosen, M.D., Series Editor
Editors
David Green, MD, PhD
Professor of Medicine Emeritus
Division of Hematology/Oncology
Feinberg School of Medicine
Northwestern University
Chicago, Illinois 60611-2927
USA

In a series of updated reviews, the contributors to this book describe the effects of cancer on coagulation and coagulation on cancer. In the first chapter, Monroe and Hoffman present
their current concept of hemostasis, with an emphasis on the cell-based mechanism they recently delineated
The treatment of the cancer patient presents certain challenges not present
in patients without malignancies. These include the risk of bleeding due to chemotherapy-induced thrombocytopenia, recurrent and refractory venous thromboembolism, and concerns about maintaining the quality of life of patients with advanced disease. In the final chapter of this section, there is an examination of the effects of anticoagulants on cancer.
The final section of the book discusses bleeding problems in cancer, beginning with a review of cancer-associated thrombocytopenia by Eklund. A diagnostic algorithm for assessing thrombocytopenia in the cancer patient is presented, and the use of platelet transfusions for patients with decreased platelet production, as proposed by the American Society of Clinical Oncology